An Israeli air strike early on Sunday has incapacitated the last fully functioning hospital in Gaza City as the military expands and intensifies its campaign across the territory.

CAIRO (Reuters) -Two Israeli missiles hit a building inside a main Gaza hospital on Sunday, destroying the emergency and reception department and damaging other structures, medics said, in a strike which Israel said was against Hamas fighters exploiting the facility.

At least 21 people, including children, were killed as the Israeli military vowed to expand its presence in the small coastal strip.