Protesters targeted several Los Angeles County hotels where ICE agents were believed to be staying overnight. A crowd of about 50 to 75 people in front of the Embassy Suites by Hilton hotel in Downey waved flags and held signs that read “DEHUMANIZE ice” into the early morning hours on Thursday.

More than 35% of Los Angeles' population is foreign-born, shaping its reaction to Trump's immigration crackdown.

The National Guard has at times detained protesters in its deployment to Los Angeles, an official said Wednesday, as demonstrations against Immigration and Customs enforcement raids spread to other major cities.

About 500 of the Guard troops deployed to the protests have been trained to accompany agents on immigration operations, he said. Sherman initially said National Guard troops had temporarily detained some civilians.

Unions have backed immigrant rights in California and have been on the forefront of resisting the Trump administration’s deportations.