Expert Rev Endocrinol Metab. 2013;8(2):183-193. Mitotane reduces cortisol synthesis through the inhibition of 11B-hydroxylase, 18-hydroxylase, 3-α hydroxylase, hydroxysteroid dehydrogenase and several ...
Cushing disease and Cushing syndrome have similar symptoms but are distinct conditions with different possible causes and treatments. It is important for people to consult a doctor for a proper ...
Agents that directly lower ACTH secretion by a pituitary adenoma represent an attractive option for the treatment of Cushing's disease, as these drugs directly target the pathogenesis of disease.