Currently, 0.4% glyceryl trinitrate rectal ointment (Rectogesic 4 mg/g rectal ointment, ProStrakan) is the only licensed treatment for chronic anal fissure in the UK. It is indicated for the relief of ...
June 22, 2011 — The US Food and Drug Administration (FDA) has approved nitroglycerin ointment 0.4% (Rectiv, ProStrakan Group) for the treatment of moderate to severe pain associated with chronic anal ...
Medical therapy is an established first-line approach for the treatment of patients with chronic anal fissure; however, the efficacy of individual agents versus placebo remains to be proven in this ...
GALASHIELS, Scotland, and BEDMINSTER, N.J., June 22, 2011 /PRNewswire/ -- ProStrakan Group plc, a subsidiary of Kyowa Hakko Kirin Co. Ltd., and an international specialty pharmaceutical company, today ...
A digital rectal exam, which may be painful, may be needed if a definitive diagnosis of anal fissures cannot be made based on a patient’s history. 1 Anoscopy, which also may be painful, can be used to ...
NEW YORK, Feb. 12, 2014 (GLOBE NEWSWIRE) -- Ventrus Biosciences, Inc. (VTUS) today announced top line efficacy and safety results from the second Phase 3 clinical trial of Diltiazem Hydrochloride 2% ...
The main adverse effect related to glyceryl trinitrate use is headache. Of particular relevance to patient care is where headache is of such severity that it leads to treatment discontinuation (Nelson ...
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