AlphaDEX Industrials index, long-term underperformance, higher volatility/drawdowns, factor tilt and 60 bps fee. See more ...

A protein that is a key modulator of fat, glucose and cholesterol levels in the body usually works in tandem with another ...

The systemic expression of the bile acid (BA) sensor farnesoid X receptor (FXR) has led to promising new therapies targeting cholesterol metabolism, triglyceride production, hepatic steatosis and ...

Nuclear receptors (NRs) are ligand-activated transcription factors that have central roles in nearly every aspect of development and adult physiology 1. This family contains 48 members in humans.

The First Trust Industrials/Producer Durables AlphaDEX ETF (FXR) made its debut on 05/08/2007, and is a smart beta exchange traded fund that provides broad exposure to the Industrials ETFs category of ...

MANITOBA, Calif.--(BUSINESS WIRE)--FXR Pro Fish, a brand driven by bringing innovation to the water, is proud to announce its partnership with the Bassmaster Elite series as the title sponsor for the ...

Eli Lilly has acquired Organovo’s lead asset, a clinical FXR agonist designed to treat inflammatory bowel disease (IBD), in a deal worth up to $50 million in biobucks. Organovo’s stock skyrocketed 244 ...

The farnesoid X receptor (FXR) is a bile acid nuclear receptor that plays a crucial role in regulating bile acid and sterol metabolism. Bile acids are natural ligands of FXR, which bind to the ...

Harley-Davidson has had some impressive bikes in its catalog in its century-long run. The motorcycle manufacturer has some of the most successful motorcycles in history, from the Softail Fat-Boy and ...

The pleiotropic actions of the Farnesoid X Receptor (FXR) are required for gut health, and reciprocally, reduced intestinal FXR signaling is seen in inflammatory bowel diseases (IBDs). Here, we show ...