Introduction Depression is a major global health challenge, with onset commonly occurring in youth. There is an urgent need to better understand the epidemiology of depression to facilitate better ...

Pathway analysis is a frequent step in studies involving gene or protein expression data, but most of the available pathway methods are designed for simple case versus control studies of two sample ...

Longitudinal data arise whenever repeated measurements are taken on the same experimental units over time or under varying conditions. Generalized estimating equations (GEE) provide a popular marginal ...

This joint-specific response pattern was consistent across all advanced treatment modalities, including abatacept, interleukin-6 receptor inhibitors, Janus kinase inhibitors, rituximab and TNFi.

Phase II study of trastuzumab-pkrb plus gedatolisib in patients with HER2-positive metastatic breast cancer who progressed after 2 or more HER2-directed chemotherapies (KM-10A/KCSG BR18-13). This is ...

Variation in environmental factors can result in changes in pavement material properties. In asphalt pavements, asphalt stiffness is affected by changes in temperature (e.g., moduli value increases ...

Clinical impact of oncogenic KRASdosage variation in pancreatic cancer. A phase II study of radiotherapy combined with docetaxel, cisplatin, and 5-fluorouracil for postoperative loco-regional ...

New research quantified the association between loneliness and dementia by analyzing data from more than 600,000 people around the world. The meta-analysis of 21 longitudinal studies showed that ...

Background Adequate education funding is important to reduce the socioeconomic inequality in educational attainment, an ...

Over the past two decades, substantial investments in aging data infrastructure have transformed East and Southeast Asia from a region characterized by fragmented data coverage into one of the better ...

The IMF’s World Revenue Longitudinal Database (WoRLD) tracks government revenue trends since the early 1980s. This invaluable resource offers policymakers, researchers, and the public crucial insights ...