Levels of C4d and C4d/C4 associate with clinical and histopathological treatment response in proliferative lupus nephritis. Complement activation markers, particularly C4d and the C4d/C4 ratio, are ...

Study focuses on interferon blocker's hematologic and serologic benefits ...

The complement system is part of the body's immune system to fight pathogens and remove cell debris; its role in two autoimmune diseases and a mental disorder is a surprise Variants in a gene of the ...

Study offers molecular explanation for long-standing observation that certain diseases occur more often or more severely in different sexes. Complement component 4 (C4) genes protect against the ...

A complement C4 (also known as a complement component 4, or simply C4) is a test to measure the level of C4 proteins you have in your blood. These proteins play a role in how your immune system ...

Most people with lupus have antinuclear antibodies (ANAs) in their blood. But a positive ANA test doesn’t always mean lupus. The test can be positive in people with other autoimmune illnesses — ...