Early in development, a group of migrating cells called cranial neural crest cells go on to form many different parts of the face, including the nose, jaw, ears, and throat. To build these structures ...
A crucial new mechanism that helps explain how the heart’s major blood vessels form during early development – and how disruptions to this process can lead to serious congenital heart defects – has ...
Craniofacial birth defects, including cleft lip and palate, are among the most common human congenital malformations. These craniofacial anomalies occur because of defects in neural crest cells, whose ...
What are the first steps that chart the path for a cell to become a blood cell, neuron cell, or pigment cell? Scientists have ...
An illustration of zebrafish heart development, showing the migration of cells in the growing embryo after 17 hours, 1 day and 2 days to form the heart. Most heart cells come from the embryonic ...
The image shows induced human neural crest cells. Human embryonic stem cells display neural crest characteristic expression after only five days of culture under WNT induction. Transcription factors ...
A new AI framework estimates how cells change over time and infers the gene regulatory networks controlling those changes.
Most of what scientists know about face development comes from studies in bony vertebrates such as mice, chickens, and zebrafish. However, their evolutionary counterparts, cartilaginous fishes, have ...