Alcohol binge increases intestinal permeability by activating intestinal epithelial CB1R-ERK1/2 signalling with subsequently reduced differentiation and downregulation of tight junctions (left).

A study published in eGastroenterology investigated the role of cannabinoid receptor 1 (CBR1) in intestinal permeability, commonly called “leaky gut.” In particular, the study focused on CBR1’s ...

Harvard Health says “leaky gut” is not a clinical diagnosis, but it’s a condition that breaks down the intestinal lining, allowing partially digested food, toxins, and microbes to escape their ...

A new study shows that a high fat diet may weaken the gut barrier and allow bacteria to travel toward the brain through the vagus nerve.

The gut rarely gets the attention the heart or brain receives. Yet it quietly controls digestion, immunity, metabolism, and even mood. Scientists now believe the gut may age faster than the rest of ...