XPD/Rad3-like helicases are critical enzymes for preserving genomic integrity across various organisms 1,2,3,4,5. These superfamily 2 helicases translocate 5ˈ to 3ˈ along ssDNA and unwind DNA/DNA and ...

Researchers from the MRC Protein Phosphorylation and Ubiquitylation Unit at the University of Dundee, together with collaborators from ETH Zürich, the Malopolska Center of Biotechnology and the ...

A new technology allows scientists to map, in single cells, the DNA binding sites of transcription factors and other regulatory proteins that control gene activity, according to a study led by ...

While the above assays indicate that UBP and MCM can interact in solution, we additionally wanted to test whether they could interact with DNA. To this end, we performed electrophoretic mobility shift ...