Thousands of years ago, a special child was born in the Sahara. At the time, this was not a desert; it was a green belt of savannas, woodlands, lakes and rivers. Bands of hunter-gatherers thrived ...

Sickle cell disease is caused by a single genetic mutation that alters the shape of red blood cells. While the condition ...

Gene therapy has the potential to dramatically benefit patients with genetic blood disorders, but a small study on participants in a clinical trial for sickle cell disease suggests that a key process ...

UCSF Benioff Children's Hospital Oakland is enrolling patients in an innovative clinical trial that seeks to cure sickle cell disease. The trial is the first in the U.S. to apply non-viral CRISPR-Cas9 ...

Subscribe to The St. Louis American‘s free weekly newsletter for critical stories, community voices, and insights that matter. Sign up When Dr. Ambroise Wonkam walked into a panel on medical genetics ...

UCSF Benioff Children's Hospital Oakland is enrolling patients in an innovative clinical trial that seeks to cure sickle cell disease. The trial is the first in the U.S. to apply non-viral CRISPR-Cas9 ...

More than a century after sickle cell disease was first diagnosed, the inherited blood disorder appears to be on the verge of a cure. That progress was kick-started, in part, by the Doris Duke ...

Beam Therapeutics’ experimental gene-editing therapy for sickle cell disease now has its first cut of patient data showing signs of treating the rare blood disorder in a way that could differentiate ...

NHS Scotland has approved a one-time CRISPR gene therapy for severe sickle cell disease, offering durable reduction in vaso-occlusive crises for eligible patients.

A new gene therapy for people who can have a stem cell transplant but do not have a suitable donor has been approved.

You might have wondered why some people with sickle cell disease seem to live relatively normal lives while others spend half their time in the hospital writhing in agony from pain crises. It’s the ...