Peptides displayed by the human leukocyte antigen (HLA) system have been subjected to unusually thorough prospecting. As a result, a mother lode of potential new targets has been uncovered for ...

Pre-mRNA splicing in a subset of human short introns is governed by a distinct mechanism involving a new splicing factor, new research finds. The interrupted non-coding regions in pre-mRNAs, termed ...

Mutually exclusive splicing is an important mechanism in a wide range of eukaryotic branches to expand proteome diversity, but the extent of its distribution within a single species and its ...

Spliced and non-spliced epitopes are produced by a complex molecular machine -- the proteasome -- und subsequently transported to the cell surface. Here, they act as tiny flags to mark cells. These ...