Glycoproteomics integrates the study of the diverse and complex glycan modifications of proteins with advanced mass spectrometry techniques. This field is instrumental in deciphering cellular ...

A common biological surface analysis technique breaks proteins up into smaller molecules that look identical. Reference spectra can help analyze these proteins for understanding diseases and creating ...

The process of protein identification typically begins with a bottom-up approach, where proteins are enzymatically digested—most commonly with trypsin—into smaller peptides. These peptides are ...

At the University of Oxford, Justin Benesch studies assemblies made between proteins called molecular chaperones and the proteins they protect in cells. These assemblies slow the formation of amyloid ...

Mass spectrometry measures the mass-to-charge ratio of ions by ionizing chemical compounds to produce charged molecules. A typical mass spectrometer consists of three parts: a detector, a mass ...

The rapid evolution of high-resolution mass spectrometry (MS) has necessitated the development of increasingly sophisticated proteomics software to translate complex spectral data into biologically ...

Researchers have developed a machine learning model called DreaMS, which significantly accelerates the analysis of previously unknown molecules. The study is published in Nature Biotechnology. The ...