Electron microscope (EM) has revolutionised our ability to visualise the intricate details inside cells. The advancement to 3D electron microcopy, known as volume EM (vEM), has further expanded this ...

Over the past two decades, correlative light and electron microscopies (CLEM), have become crucial for deciphering biological complexities across scales. A pivotal aspect of this workflow is the ...

Stretching protein samples in all directions pulls molecules farther apart, allowing them to be visualized using only light ...

Now, in a recently published Journal of Cell Biology paper, scientists used a newer electron microscopy technique, called volume electron microscopy (vEM), to examine how primary cilia on developing ...

Cryo-electron microscopy (cryo-EM) can help scientists determine the three-dimensional structure of proteins in unprecedented detail. Jacques Dubochet, former group leader at EMBL, shared the 2017 ...

Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which ...

ST. LOUIS, MO February, 25 2025 – Danforth Center scientists Tessa Burch-Smith, PhD, and Kirk Czymmek, PhD, in collaboration with researchers at the CryoEM Facility at Stanford University, are ...

Microscopy is an imaging technique that enables us to see a world that would otherwise be invisible to us. Once upon a time, visualizing cells, microbes and other entities not perceptible to the naked ...

Explore how the National Lab of the Rockies uses advanced microscopy, cryogenic workflows, and automation to connect ...