Johnson & Johnson (NYSE: JNJ) today announced the submission of a supplemental Biologics License Application (sBLA) to the U.S. Food and Drug Administration (FDA), seeking approval of IMAAVY® ...

Sanofi’s rilzabrutinib designated breakthrough therapy in the US and orphan drug in Japan for the treatment of warm autoimmune hemolytic ...

Mihir Raval, MD, MPH, comments on the difference between cold agglutinin disease and other autoimmune hemolytic anemias. Neil Minkoff, MD: Now, you had mentioned that there are other autoimmune ...

Cold antibody hemolytic anemia is a rare autoimmune disorder characterized by the premature destruction of red blood cells by autoantibodies at temperatures of approximately 0 to 10 degrees Celsius. Q ...

The following report presents 3 cases of intravascular hemolysis that followed aortic-valve replacement with cusps composed of Dacron cloth impregnated with silicone rubber. 8,9 Hematologic data on 32 ...

Autoimmune hemolytic anemia (AIHA) and paroxysmal nocturnal hemoglobinuria (PNH) are distinct blood disorders with different underlying causes and treatment approaches. Each is rare and potentially ...

The patient in the case reported below received no sulfonamide. The clinical and experimental data indicate that exposure and diffuse chilling were instrumental in producing the anemia. These data are ...

Breakthrough Therapy status for rilzabrutinib in wAIHA addresses the lack of approved treatments for this rare and life-threatening condition.

Physical/chemical causes. These causes of hemolysis are most often secondary to improper handling of blood products. Reasons include inadvertent heating or freezing with subsequent thawing of the red ...

CAR T-cell therapies are now being used to treat patients with B-cell driven autoimmune diseases such as lupus. Another such condition is autoimmune hemolytic anemia, in which immune cells destroy red ...

Bone marrow transplantation (BMT) has occasionally been complicated by the development of hemolytic anemia from specific alloantibodies to either ABO or Rh antigens. We report a case of post-BMT ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, No. 8 (Apr., 1990), pp. 3117-3121 (5 pages) Mice with normoblastosis, nb/nb, have a severe hemolytic anemia.