Journal of Epidemiology and Community Health (JECH)

Guide to recent advances in difference-in-differences methodology for population health studies

Background Difference-in-differences is a method commonly used in population health research. It is based on assumptions that ...
BMJ

Interpreting p values and interval estimates based on practical relevance: guidance for the sports medicine clinician

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be ...
Nature

Statistical Methods for Multiple Hypothesis Testing

When researchers conduct many statistical tests simultaneously, the chance of obtaining false positives increases. Traditional methods for multiple comparisons, such ...
Frontiers

Null hypothesis significance testing vs. Bayesian inference using generalized linear mixed models with binary outcomes: a case study under practical design constraints

Empirical investigation requires dealing with fundamental uncertainty. In experimental psychology, research questions are often addressed using Null Hypothesis Significance Testing (NHST), an approach ...
RAPS

EMA proposes new method to reduce animal drug testing

Following the trend of other regulators, the European Medicines Agency (EMA) is taking steps to reduce the need for animal testing. The agency has issued a draft qualification opinion for a new ...
Reuters

US FDA pushes for new methods to replace animal testing in early drug studies

March 18 (Reuters) - The U.S. Food and Drug Administration on Wednesday issued a draft guidance to help companies reduce animal studies of experimental drugs and adopt newer methods, such as computer ...
IEEE

Multiple Hypothesis Testing for Anomaly Detection in Multi-type Event Sequences

Abstract: Anomaly detection in multi-type event sequences is a crucial and challenging problem with important applications in various domains, including cybersecurity, finance and healthcare. Temporal ...
Gizmodo

Simple Blood Test Can Predict Dementia 25 Years in Advance, Study Suggests

The blood biomarker p-tau217 has "shown the most promise in detecting Alzheimer's in the brain," researchers of a new study say. Reading time 3 minutes Your blood might someday reveal much about the ...
MIT Technology Review

The first human test of a rejuvenation method will begin “shortly”

In a bid to treat blindness, Life Biosciences will try out potent cellular reprogramming technology on volunteers. When Elon Musk was at Davos last week, an interviewer asked him if he thought aging ...
The New York Times

E.P.A. Promises a Ban on Animal Testing by 2035

Lee Zeldin, the E.P.A. administrator, revived a plan created during the first Trump administration to end the testing of chemicals on mammals. By Lisa Friedman The Environmental Protection Agency will ...
The New York Times

Trump’s E.P.A. Has Put a Value on Human Life: Zero Dollars

The Environmental Protection Agency has stopped estimating the dollar value of lives saved in the cost-benefit analyses for new pollution rules. Los Angeles smog in 1979. For decades, government ...
Medscape

P-tau217 Blood Test Can Identify Preclinical AD in Asymptomatic Patients

Plasma measures of phosphorylated tau217 (p-tau217) can accurately identify individuals in the preclinical stage of Alzheimer’s disease (AD), a new meta-analysis showed. The results are important ...