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Background Increased rates of brain atrophy on serial MRI are frequently used as a surrogate marker of disease progression in Alzheimer’s disease and other dementias. However, the extent to which they ...
The concept of antibody mediated CNS disorders is relatively recent. The classical CNS paraneoplastic neurological syndromes are thought to be T cell mediated, and the onconeural antibodies merely ...
Correspondence to: Dr Patricia A McKinney Paediatric Epidemiology Group, Unit of Epidemiology and Health Services Research, University of Leeds, 32 Hyde Terrace, Leeds LS2 9LN, UK; ...
Correspondence to Elisa Colato, Russell Square House, 10-12 Russell Square, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, ...
Background Human neural stem cell implantation may offer improved recovery from stroke. We investigated the feasibility of intracerebral implantation of the allogeneic human neural stem cell line ...
Correspondence to Dr Frederik J Steyn, Centre for Clinical Research, The University of Queensland, Brisbane, QLD 4072, Australia; f.steyn{at}uq.edu.au This male patient was first seen at age 62 years ...
Two cases of anterior spinal hernia are presented. The medical literature is reviewed, the syndrome characterised, and its cause and treatment discussed. The patient is typically middle aged with a ...
Objective Myelin oligodendrocyte glycoprotein-associated disorders (MOGADs) are a rare new neurological autoimmune disease with unclear pathogenesis. Since a linkage of the disease to the human ...
Background/objective: Little is known about the long-term clinical course and management of patients with normal pressure hydrocephalus (NPH) treated by cerebrospinal fluid (CSF) shunting. Methods: We ...
Background: m.14487T>C, a missense mutation (p.M63V) affecting the ND6 subunit of complex I of the mitochondrial respiratory chain, has been reported in isolated childhood cases with Leigh syndrome ...
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