UC Santa Cruz scientists, along with a consortium of researchers, have released a draft of the first human pangenome — a new, usable reference for genomics that combines the genetic material of 47 ...

Researchers have released a new high-quality collection of reference human genome sequences that captures substantially more diversity from different human populations than what was previously ...

As next-generation sequencing technologies produce deeper genome coverages at lower costs, there is a critical need for reliable computational host DNA removal in metagenomic data. We find that ...

The original reference human genome sequence, now almost two decades old, is limited in its representation of the diversity of the human species as it consists of genomes from only about 20 people, ...

The Human Pangenome Reference Consortium has announced the first draft of a human ‘pangenome’, which incorporates DNA data from 47 individuals. The Human Pangenome Reference Consortium has used ...

The human reference genome has always been a remarkable but flawed tool. A new 'pangenome' aims to correct its oversights and omissions. For more than 20 years, scientists have relied on the human ...

Stem cell-based embryo models offer unprecedented experimental tools for studying early human development. The usefulness of embryo models hinges on their molecular, cellular and structural fidelities ...

For decades, the Y chromosome — one of the two human sex chromosomes — has been notoriously challenging for the genomics community to sequence due to the complexity of its structure. Now, this elusive ...

In a new study published in Nature Communications titled, “The reference genome of the human diploid cell line RPE-1,” researchers from University of Rome La Sapienza have produced the first reference ...

Scientists have released a draft of the first human pangenome -- a new, usable reference for genomics that combines the genetic material of 47 individuals from different ancestral backgrounds to allow ...