Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

Obesity is considered a major public health epidemic that affects an estimated 600 million people or more around the world... | Microbiology ...

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

Salts of 12-hydroxystearate are important organogelators and grease thickeners, but a structural rationale for their rheological properties remains elusive. We use quantum mechanical calculations and ...

The Section maintains and operates several global isotope data networks for hydrology and climate studies, including the IAEA Global Network of Isotopes in Precipitation and the Global Network of ...

Water plays a crucial role in determining the functions of biomolecules and nanomaterials. However, the electronic structure of water molecules at the nanoscale remains elusive. In this study, we ...

LyondellBasell (Rotterdam, the Netherlands; www.lyondellbasell.com) today announced that it has entered into an agreement and exclusive negotiations with AEQUITA (Munich, Germany; www.aequita.com) for ...