Neither the Seattle Seahawks nor the Detroit Lions are going to be at full strength for their clash on Monday Night Football this week. The biggest name that will be out for Detroit will be starting center Frank Ragnow,

Williams has been credited with six tackles, eight quarterback hits, 1.5 sacks, and 11 pressures in three games, per Pro Football Focus. Murphy has been credited with four solo tackles, one sack, six QB hurries, and seven pressures. Losing either one, let alone both, would represent a significant blow to Macdonald’s defensive line.

Decimated by injuries along the defensive line, the Seahawks will have to face a physical Lions squad without three starters, including Boye Mafe.