The San Francisco 49ers have been great after their bye week since Kyle Shanahan took over, but they struggled in 2024.

Aiyuk, 27, has not played a down of football since injuring his ACL and MCL in the 49ers' 28–18 loss to the Chiefs in Week 7 ...

Brandon Aiyuk hasn't played an NFL game since his serious knee injury in 2024. Here's why he won't be playing at all in 2025.

The on-again, off-again relationship between wide receiver Brandon Aiyuk and the San Francisco 49ers looks to be off again.

The San Francisco 49ers on Saturday placed Brandon Aiyuk on the reserve/left squad list, ending his 2025 season and likely ...

The San Francisco 49ers are officially one of the legitimate playoff contenders. They are almost locks to make the playoffs, ...

The San Francisco 49ers have placed receiver Brandon Aiyuk on the reserve/left squad list, making him ineligible to return ...

The details of Aiyuk's four-year, $120 million contract include $24.9 million option bonus for 2026 that fully guaranteed on ...

San Francisco 49ers running back Christian McCaffrey is now questionable to play and that means it's time to grab backup ...

San Francisco 49ers running back Christian McCaffrey has been added to the injury report on Saturday with a back issue.

That 2023 Niners team reached the Super Bowl, and expectations have been high since, but San Francisco has mirrored McCaffrey ...

The San Francisco 49ers announced on Saturday that running back Christian McCaffrey has been downgraded to questionable for Week 15.