Gut1d
Tumour-intrinsic alterations and stromal matrix remodelling promote Wnt-niche independence during diffuse-type gastric cancer progression
Background Development of diffuse-type gastric cancer (DGC) starts with intramucosal lesions that are primarily composed of ...
gut.bmj3d
British Society of Gastroenterology (BSG) guidelines for management of autoimmune hepatitis
Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease which, if untreated, often leads to cirrhosis, liver failure and death. Major advances were made in its management based on ...
gut.bmj2d
Inflammatory bowel diseases among first-generation and second-generation immigrants in Denmark: a population-based cohort study
Objective Our objective was to estimate the relative risk of IBD among first-generation and second-generation immigrants in Denmark compared with native Danes. Design Using national registries, we ...
gut.bmj3d
Intron-mediated enhancement of SPINK1 expression for pancreatitis therapy
Correspondence to Dr Miklós Sahin-Tóth, Department of Surgery, University of California Los Angeles, Los Angeles, California, USA; msahintoth{at}mednet.ucla.edu Here, using a cell culture model, we ...
gut.bmj5d
Chronic gastritis, alcohol, and non-ulcer dyspepsia
An investigation of 102 men comprising alcoholics, patients with non-ulcer dyspepsia, and healthy controls is reported. It demonstrates that alcohol is a cause of chronic gastritis and the severity of ...
gut.bmj6d
Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment
Objective Pancreatic ductal adenocarcinoma (PDAC) shows a remarkable predilection for liver metastasis. Pro-oncogenic secretome delivery and trafficking via exosomes are crucial for pre-metastatic ...
gut.bmj6d
PWE-121 Comparison Of Kings Score, Apri and AST/ALT Ratio in Determining Severity of Liver Disease Versus Liver Biopsy
Introduction Background and Aims Non-invasive markers of liver fibrosis are used to stratify the severity of Liver disease. The aim of the study was to compare the accuracy of the AST/ALT ratio, ...
gut.bmj6d
Hypertension is an independent risk factor for colorectal polyps
Introduction Components of metabolic syndrome including obesity and insulin resistance with colorectal neoplasia have been well characterised, but the association of other cardiovascular risk factors ...
gut.bmj6d
Diverse tumour susceptibility in Collaborative Cross mice: identification of a new mouse model for human gastric tumourigenesis
Objective The Collaborative Cross (CC) is a mouse population model with diverse and reproducible genetic backgrounds used to identify novel disease models and genes that contribute to human disease.
gut.bmj6d
Protein kinase D2 is a crucial regulator of tumour cell–endothelial cell communication in gastrointestinal tumours
5 Department of Molecular Cell Biology, K.U. Leuven, Belgium 6 Vesalius Research Center (VRC), Belgium 7 Department of Internal Medicine 1, Martin-Luther-University Halle-Wittenberg, Germany ...
gut.bmj4d
Hydrogen peroxide enhanced ultrasound- fistulography in the assessment of enterocutaneous fistulas complicating Crohn's disease
Professor G Bianchi Porro, Department of Gastroenterology, L Sacco University Hospital, Via G B Grassi, 74, 20157 Milan, Italy. BACKGROUND/AIMS Proper management of enterocutaneous fistulas ...