Background Women with left ventricular outflow tract obstruction (LVOTO) are at risk of adverse pregnancy outcomes, which ...

Background Drug-coated balloon (DCB) angioplasty has emerged as a potential stent-free strategy for percutaneous coronary intervention (PCI) in de novo coronary artery disease, but robust randomised ...

Cancer therapy has dramatically changed over the past many decades, not only in efficacy but also complexity, with targeted ...

Congenital heart disease (CHD) is the most common congenital anomaly, with lifelong implications as survival into adulthood becomes the norm. Despite advances in prenatal detection, surgical care and ...

Ventricular tachycardia (VT) is an abnormal rapid heart rhythm that most commonly occurs in the setting of ventricular scar. In patients with ischaemic cardiomyopathy and VT, the most common mechanism ...

Background Artificial intelligence ECG (AI-ECG) models can predict cardiovascular outcomes, but their clinical adoption is limited by restricted access to training data and uncertain generalisability.

A 54-year-old woman presented with progressive exertional dyspnoea two decades after surgical closure of an atrial septal defect (ASD). Transthoracic echocardiography demonstrated moderate tricuspid ...

A 23-year-old man with a 4-year history of recreational hallucinogenic drug misuse presented with a 3-week history of dyspnoea and lower limb swelling but denied chest pain. He reported no recent ...

Original research: Isolated non-specific electrocardiographic ST-T abnormalities and risk of incident heart failure and its subtypes (17 November, 2025) ...

Background Pilots face significant occupational risks affecting cardiometabolic health and are subject to regulatory health screenings. Cardiometabolic risk factors, cardiac screening findings and ...

Correspondence to Dr Seamus P Whelton, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA; seamus.whelton{at}jhmi.edu Coronary artery calcium (CAC) is a direct measure of an individual’s ...