Proteolysis targeting chimera (PROTAC) technology has emerged as a powerful tool in drug discovery that enables targeted protein degradation through a unique bifunctional approach. This review ...

In vivo, in rats with ventricular fibrillation (VF)-induced CA, a selective cGAS inhibitor (RU.521) was used to specifically inhibit cGAS activity, thereby blocking its downstream signaling pathway.

Tumor ferroptosis, a regulated form of cell death driven by iron-dependent lipid peroxidation, has emerged as a promising therapeutic strategy for combating cancers, particularly in cases involving ...

Objective: The goal of this study was to examine the prognostic performance of optical flow ratio (OFR) among patients with coronary artery disease (CAD) after percutaneous coronary intervention (PCI) ...

In the field of education, inclusion is the process of integrating students with disabilities into mainstream classrooms, thereby guaranteeing that they have equal opportunities to learn and ...

The heart is the central organ of the human circulatory system. Both congenital and acquired structural changes in the heart can lead to hemodynamic alterations affecting the function of various ...

Scrub typhus, caused by Orientia tsutsugamushi, is a vector-borne, zoonotic disease commonly occurring in a geographic region known as the ‘tsutsugamushi triangle’. Scrub typhus causes acute ...

Radiation-induced cardiomyopathy has become a significant clinical challenge with the increased use of thoracic radiation therapy. Recent technological advancements in radiation therapy, such as 3D ...

Background: With distal transradial access (dTRA), the postoperative compression time remains significantly longer than the recommended range via in practice. This study investigated whether ...

Mental health disorders (MHDs) have significant medical and financial impacts on patients and society. Despite the potential opportunities for artificial intelligence (AI) in the mental health field, ...