The discovery could lead to a new treatment for millions of people with obesity and type 2 diabetes who do not respond well to current treatments.

Dozens of rugby players were joined by Red Roses internationals to celebrate the Women’s World Cup coming to Brighton in 2025.

The UK and Romania have signed a defence treaty as the two nations continue their efforts to support war-torn Ukraine. Defence Secretary John Healey and his counterpart, Angel Tilvar, signed the ...

Tomatoes could be engineered to be sweeter without sacrificing their size, research suggests. Experts said that most consumers prefer sweeter tomatoes and higher sugar content increases the value of ...

Shadow equalities minister Claire Coutinho has pressed the Government to clarify the definition of sex. Equalities minister Bridget Phillipson said it was “important that providers have clarity in ...

Council tax bills in England are expected to increase by up to 5% next April, amid Tory warnings that local authorities face a £2.4 billion “black hole”. Conservative Party leader Kemi Badenoch ...

Sara Sharif’s father has confessed to killing the 10-year-old but insisted he did not mean to “harm” her when he bound and beat her with a cricket bat. Taxi driver Urfan Sharif, 42, had sought to ...

US President Joe Biden will welcome President-elect Donald Trump to the White House for an Oval Office visit that is a ...

Four Sussex Post Offices are under threat of closure in a major overhaul. The Post Office has announced that 115 branches are at risk of closure or transfer to other retail partners or postmasters, ...

An 18-year-old man accused of killing three young girls in a knife attack at a dance class in Southport and producing the deadly toxin ricin will go on trial next year. Axel Rudakubana covered his ...

The UK Government announced its decision to relinquish sovereignty over the Chagos Islands to Mauritius last month.

Smith, of Hart Dyke Road in Swanley, Kent, was charged with dangerous driving, aggravated vehicle taking, going equipped for theft, fraudulent use of a vehicle registration mark, possession of a knife ...