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  1. Hydroxymethylbutyrate (HMB): Benefits, Downsides, and More

    Apr 28, 2021 · HMB is a substance your body produces naturally when it breaks down the amino acid leucine. It may offer benefits as a supplement, possibly helping reduce muscle loss or increasing …

  2. Hydroxymethylbutyrate (HMB): Overview, Uses, Side Effects ...

    It can be found naturally in small amounts in grapefruit, alfalfa, and catfish. It's also naturally made in the body. People use HMB for building muscle or preventing age-related muscle loss.

  3. HMB benefits, dosage, and side effects - Examine

    Sep 4, 2025 · HMB is a metabolite of the essential amino acid leucine that plays an anticatabolic role in muscle tissue. In addition to preventing muscle protein breakdown, HMB may help improve strength …

  4. Hydroxymethylbutyrate (HMB): Benefits and Side Effects - Health

    Dec 9, 2025 · Hydroxymethylbutyrate (HMB) benefits muscle strength and recovery. It lowers exercise-induced muscle damage and may slow muscle wasting in older adults.

  5. β-Hydroxy β-methylbutyric acid - Wikipedia

    β-Hydroxy β-methylbutyric acid[note 1] (HMB), otherwise known as its conjugate base, β-hydroxy β-methylbutyrate, is a naturally produced substance in humans that is used as a dietary supplement …

  6. HMB: What You Should Know from a Dietitian, PhD | GNC

    Feb 18, 2025 · HMB was first discovered in the 90s by Dr. Naji Abumrad and Dr. Steven Nissen. Through their initial research they discovered a metabolite of leucine which activates protein …

  7. Home - myHMB®

    The pure free acid form of HMB designed for faster absorption and superior bioavailability to maximize muscle health benefits for all ages and activity levels. A synergistic combination that enhances …